Clinical Guidelines

BHOF's Clinician's Guide to Prevention and Treatment of Osteoporosis

BHOF's Clinician's Guide contains updated guidance on vertebral fracture assessment and the use of biochemical markers of bone turnover, as well as updated information on calcium, vitamin D and medications. This useful guide is a must to inform clinical decision-making to manage the diagnosis and treatment of men and women at high risk for fractures and was recently published online by Osteoporosis International.

Single copies of this document, in its entirety or in part, may be printed and distributed for educational use. Unmodified excerpts of the text may be used for educational presentations and publications, in electronic form and in print, provided the source is attributed to the National Osteoporosis Foundation.

No part of this Guide may be reproduced with modified content without advance written permission from the Bone Health and Osteoporosis Foundation. To request permission, contact BHOF at (703) 647-3010. More information can be found on our Reprint Policy page.

Update schedule: BHOF will consider updated content to this document periodically and publish updates on an annual basis or when otherwise indicated for new FDA-approved pharmacologic agents.

The Clinician's Guide to Prevention and Treatment of Osteoporosis Mobile App

The Bone Health & Osteoporosis Foundation (“BHOF”), together with AvoMD, a software platform that translates clinical evidence into the workflow, has developed a decision support toolkit to support clinicians in the prevention, risk assessment, and treatment of osteoporosis and osteoporotic fractures.

The clinical decision support tool, developed by  BHOF with support from AvoMD, is intended for use by primary care providers and specialists assisting in the treatment and management of osteoporosis, such as rheumatologists, endocrinologists, geriatricians, and orthopedists.

Download for iPhone/iPad

Download for Android Devices


NOF/ISCD Recommendations FRAX Implementation Guide

A guide from NOF and the International Society for Clinical Densitometry with recommendations to help DXA manufacturers with FRAX® implementation.


Joint Guidance on Osteoporosis Management in the Era of COVID-19

This document provides joint guidance on osteoporosis management in the era of COVID-19 from the American Society for Bone and Mineral Research (ASBMR), American Association of Clinical Endocrinologists (AACE), Endocrine Society, European Calcified Tissue Society (ECTS) and National Osteoporosis Foundation (NOF).


Temporary Prolia® (denosumab) Injection, for subcutaneous use, Administration by Patient or Caregiver During COVID-19 Public Health Emergency


ISCD Official Adult Positions for BMD Testing

Find The International Society For Clinical Densitometry (ISCD) Adult Official Positions updated in 2019.


Own the Bone

Developed by the American Orthopaedic Association, Own the Bone is a quality improvement program to address the osteoporosis treatment gap and prevent subsequent fragility fractures.


Johns Hopkins Menopause Guide

The Johns Hopkins Menopause Guide aims to improve the care of women undergoing menopause. Developed by experts at Johns Hopkins Medicine, the Guide helps healthcare providers of all disciplines practice menopause medicine as well as support the health and wellness of aging women.


We've compiled links to external resources providing additional information on a variety of osteoporosis and bone health topics that complement the information found on the BHOF and BoneSource websites.